The Short and Long-Term Etizolam Effects to Be Aware of

Medically Reviewed

Etizolam is a thienodiazepine that is similar to benzodiazepines in structure.

Some short-term effects to expect are drowsiness, shaking, and changes to libido. Long-term effects may include withdrawal symptoms after prolonged use, as mentioned by the World Health Organization

Buying benzodiazepines, or similar drugs, without a prescription is unlawful and could result in legal consequences, such as fines or jail time. It is also risky. In March 2018, BBC News reported that teenagers trying to buying Xanax illicitly wound up with etizolam instead.

Who Uses Etizolam?

The U.S. Drug Enforcement Administration (DEA) explains that etizolam is legal in Japan, Italy, and India. Its use in the United States and Europe is not legal. Most American or European consumers encounter etizolam when trying to buy other benzodiazepines illicitly.

The BBC reports that drug dealers often dye etizolam tablets and repackage them as benzodiazepines such as Xanax. Per the DEA, etizolam is found as a powder, tablet, or on blotter paper.

In countries where its use is legal, etizolam is available in tablets containing 0.25 mg, 0.5 mg, and 1 mg of the medication.

How it Works

Etizolam became available in Japan in 1983 as a treatment for anxiety or sleep disorders.

As stated by the DEA, etizolam is a sedative, muscle relaxant, antipsychotic, and anticonvulsant. This medication is between six and 10 times stronger than other benzodiazepines, such as diazepam (Valium). 

The Following Are Commonly Reported Side Effects of Etizolam:

  • Depression
  • Confusion
  • Headache
  • Lack of coordination
  • Visual disturbances

Short-Term Effects 

In September 2017, the United States Department of Justice (USDOJ) reported that etizolam is known to depress the central nervous system (CNS). This relieves feelings of anxiety. Studies in Italy show that etizolam is efficient in relieving symptoms of depression and anxiety.

It works on gamma-aminobutyric acid (GABA) receptors that can cause you to feel more relaxed, but it may make you sleepy, have slurred speech, and lose your coordination as a result.

Long-Term Effects 

The most dangerous effect of long-term etizolam use is a dependency. As explained by WHO, dependence on etizolam is rare, but it is possible.

Research on the long-term effects of etizolam is scarce, but research on benzodiazepines can provide us with a good guess on what happens. In November 2010, Psychology Today reported that concerns about long-term use of benzodiazepines surfaced as early as the 1970s.

A few possible consequences of long-term use of these medications are:

  • Loss of coordination
  • Symptoms of withdrawal, such as depression and irritability
  • Dependence

Psychology Today also mentions that benzodiazepines have the potential for misuse and addiction.

In November 2014, the Indian Journal of Pharmacology published a case study about a patient who was addicted to etizolam. The case study highlights that etizolam is linked to the development of skin lesions and eye twitching.

Etizolam use is associated with uncomfortable symptoms of withdrawal. You may need help from a physician who can help you taper from the medication.

Is it Possible to Reverse Effects of Use?

If you have been using etizolam for recreational or other reasons, it is possible to taper your dose as you would a benzodiazepine. The World Health Organization cites literature about cases in which patients have tapered off etizolam by decreasing it in gradual increments.

USDOJ warns that not all of the etizolam’s effects or consequences are reversible.

As stated by the National Institute on Drug Abuse (NIDA), repeated use of a substance can trigger changes in the brain. Regular use of any substance often results in rewiring the brain’s reward system to trigger addiction, a chronic disorder that can only be managed with proper treatment.

A person that is addicted to etizolam or other substances will experience changes in the brain’s reward system. Your reward system consists of the parts of the brain that govern impulse control, planning, and goal-setting.

In September 2014, Harvard Medical School stated that prolonged use of benzodiazepines could increase your risk of being diagnosed with Alzheimer’s disease. Etizolam’s similarity to benzodiazepines means you can expect this to be a risk.

A Few Ways To Diminish Your Risk Are:

  • Stop use of etizolam within three months, if you live in a country where it is legal.
  • Avoid long-term use of any benzodiazepine or a similar drug.

Patients who stop using etizolam or any other benzodiazepine within the first three months of use are at a decreased risk of brain damage or misuse. Other risk factors for irreversible brain damage include your age and the dosage level.

Etizolam is not legal to import, own, or use in the United States. You could face legal consequences for possessing it.

Tap to GET HELP NOW: (844) 326-4514